Brain inclusions mainly composed of misfolded and aggregated TAR DNA binding protein 43 (TDP-43), are characteristic hallmarks of amyotrophic lateral sclerosis (ALS).Irrespective of the role played by the inclusions, their reduction represents an important therapeutic pathway that is worth exploring.Their removal can either lead to the recovery of
Abstract Background Hi-C data have been widely used to reconstruct chromosomal three-dimensional (3D) structures.One of the key limitations of Hi-C is the unclear relationship between spatial distance and the number of Hi-C contacts.Many methods used a fixed parameter when converting the number of Hi-C contacts to wish distances.However, a single p
This study examined two things: a) challenges confronting undergraduate students as a result of an abrupt transition to online learning in response to the COVID-19 pandemic, and b) the coping techniques that they employed to tackle the challenges.Using Google Forms, interviews were conducted with 418 undergraduate students in one of universities in
Abstract Locomotive Today, wireless sensor networks (WSNs) are growing rapidly and provide a lot of comfort to human life.Due to the use of WSNs in various areas, like health care and battlefield, security is an important concern in the data transfer procedure to prevent data manipulation.Trust management is an affective scheme to solve these probl
With the goal of assessing the capability of Computational Fluid Dynamics (CFD) to simulate combustion instabilities, the present work considers a premixed, bluff-body-stabilized combustor with well-defined inlet and outlet boundary conditions.The present simulations produce flow behaviors in good Tie Back qualitative agreement with experimental ob